Tractography-Enhanced Biopsy of Central Core Motor Eloquent Tumours: A Simulation-Based Study
Published in: Journal of Personalized Medicine
Authors: Harishchandra Lalgudi Srinivasan; Jose Pedro Lavrador; Kantharuby Tambirajoo; Graeme Pang; Sabina Patel; Richard Gullan; Francesco Vergani; Ranjeev Bhangoo; Jonathan Shapey; Ahilan Kailaya-Vasan; Keyoumars Ashkan
Year: 2023
Publication details: 13(3):467
DOI: 10.3390/jpm13030467
Publication type: Journal article
Topic: Brain tumour biopsy, tractography, motor eloquent tumours, corticospinal tract, surgical planning
Simple summary
This simulation study looks at whether tractography can improve planning for biopsies of tumours close to important movement pathways. It supports content on careful preoperative planning, image guidance and reducing risk when operating near eloquent brain areas.
Mr Kailaya-Vasan’s involvement
Mr Kailaya-Vasan, consultant neurosurgeon and neurovascular surgeon, is listed as a contributing author on this publication.
Published abstract
The following abstract is reproduced from the original publication and is provided for reference. It may include technical terminology intended for clinical or academic audiences.
Safe trajectory planning for navigation guided biopsy (nBx) of motor eloquent tumours (METs) is important to minimise neurological morbidity. Preliminary clinical data suggest that visualisation of the corticospinal tract (CST) and its relation to the tumour may aid in planning a safe trajectory. This single centre cross-sectional study included 10 patients with METs divided into tractography-enhanced and anatomy-based groups. Volunteer neurosurgical trainees planned biopsy trajectories, and 190 trajectories were analysed. Tractography-enhanced planning required shorter planning time, fewer trajectory and lobe changes, and produced a better trajectory safety index. The authors concluded that biopsy planning for motor eloquent tumours may be achieved in less time with a safer trajectory if tractography imaging is available.
Disclaimer
This publication page is provided for general information about Mr Kailaya-Vasan’s academic work. It is not medical advice and should not be used to guide individual diagnosis or treatment decisions. Patients should discuss their individual symptoms, diagnosis and treatment options with a specialist.