Middle Frontal Gyrus and Area 55b: Perioperative Mapping and Language Outcomes
Published in: Frontiers in Neurology
Authors: Sally Rosario Hazem; Mariam Awan; Jose Pedro Lavrador; Sabina Patel; Helen M. Wren; Oscar Lucena; C. Semedo; Hassna Irzan; A. Melbourne; Sebastien Ourselin; Jonathan Shapey; Ahilan Kailaya-Vasan; Richard Gullan; Keyoumars Ashkan; Ranjeev Bhangoo; Francesco Vergani
Year: 2021
Publication details: '12:646075
DOI: 10.3389/fneur.2021.646075
Publication type: Journal article
Topic: Awake craniotomy, language mapping, brain tumour surgery, area 55b, nTMS
Simple summary
This publication explores language mapping during awake brain tumour surgery, focusing on the middle frontal gyrus and area 55b. It supports website content about advanced functional mapping, language preservation and careful planning for tumours near eloquent brain regions.
Mr Kailaya-Vasan’s involvement
Mr Kailaya-Vasan, consultant neurosurgeon and neurovascular surgeon, is listed as a contributing author on this publication.
Published abstract
The following abstract is reproduced from the original publication and is provided for reference. It may include technical terminology intended for clinical or academic audiences.
Background: The simplistic approaches to language circuits are continuously challenged by new findings in brain structure and connectivity. The posterior middle frontal gyrus and area 55b have gained renewed interest in the language network. Methods: This retrospective single-centre cohort study included patients who underwent awake craniotomy for tumour resection. Navigated transcranial magnetic stimulation, tractography and intraoperative findings were correlated with language outcomes. Results: Sixty-five awake craniotomies were performed between 2012 and 2020, and 24 patients were included. The study found mapping responses in frontal language-related regions and concluded that the posterior middle frontal gyrus, including area 55b, is an important integration cortical hub for dorsal and ventral streams of language.
Disclaimer
This publication page is provided for general information about Mr Kailaya-Vasan’s academic work. It is not medical advice and should not be used to guide individual diagnosis or treatment decisions. Patients should discuss their individual symptoms, diagnosis and treatment options with a specialist.